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Technology
Access Business
Graffinity offers numerous 
benefits
to its customers on a straightforward
fee-for-service
basis with no downstream obligations. The client provides target
material, Graffinity will perform the fingerprint and active
compounds are designed based on a comprehensive SAR analysis.
As a result of a 3-months project Graffinity delivers an agreed
upon number of compounds to its clients for secondary assays.
Cooperations
Going forward, Graffinity is actively seeking to collaborate
with leading pharmaceutical and biotechnology companies in order
to realize the full potential of its drug discovery paradigm.
The Company employs a flexible business model which allows it
to tailor programs to the specific needs of each
partner.
RAISE process delivers
• Window to novel, diverse chemistry
• Fragments and low affinity binders built the basis for
novelty
• Novel binding modes can be characterized early
• Fastest read on drug-ability of targets
• Earliest look at SAR that is technically possible
• Scalable technology and process to any number of targets |
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• Various metabolic enzymes
• Kinases
(full
length, catalytic domains)
• Proteases
• Protein-protein interaction targets
• Esterases
• Nuclear hormone receptors
• RNA polymerases
• Total 60 targets successfully tested
since
2004. |
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